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Alpha-Lipoic Acid: This antioxidant combats inflammation and slows down aging, promoting healthier skin cells and offering protection from daily skin stressors

Interestingly, this residue is conserved in Class B1 GPCRs, such as glucagon, vasoactive intestinal peptide (VIP), and glucagon-like peptide-1 (GLP-1) (Liu et al., 2025)

But Lilly has to be considered the biggest beneficiary, as its drug tirzepatide, marketed as Mounjaro for type 2 diabetes and Zepbound for obesity, became the world's best-selling drug late last year, surpassing Keytruda, a cancer treatment manufactured by Merck